Unexpected Survival of Neurons of Origin of the Pyramidal Tract after Spinal Cord Injury
نویسندگان
چکیده
منابع مشابه
Unexpected survival of neurons of origin of the pyramidal tract after spinal cord injury.
There is continuing controversy about whether the cells of origin of the corticospinal tract (CST) undergo retrograde cell death after spinal cord injury (SCI). All previous attempts to assess this have used imaging and/or histological techniques to assess upper motoneurons in the cerebral cortex. Here, we address the question in a novel way by assessing Wallerian degeneration and axon numbers ...
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Objective(s): To reach an evidence-based knowledge in the context of the temporal-spatial pattern of neuronal death and find appropriate time of intervention in order to preserve spared neurons and promote regeneration after traumatic spinal cord injury (TSCI). Materials and Methods: The study design was based on Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA)-guided...
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Spinal cord injury (SCI) actuate to complex cellular and molecular interactions within the central nervous system in a heave to repair the initial tissue damage. The pathophysiology of acute spinal cord injury (SCI) involves primary and secondary mechanisms. Neuroinflammation is an important secondary injury process in SCI. The local inflammatory microenvironment within the injured spinal cord ...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2010
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1433-10.2010